Figure 2. Characterization of FN up-regulated during TGFβ1-induced EMT in human lung carcinoma cells.
A549 cells (A and B) and NCI-H358 (C and D) were cultured and treated as described in M&M. Cell lysates (10 µg protein) were analyzed by SDS/PAGE and Western blot. Total FN, norFN and onfFN were detected with mAbs EP5, YKH1 and FDC6, respectively; Together with GAPDH used as loading control. Representative results from triplicate experiments are shown (A and C). Signal intensities were normalized, and relative intensities are shown as mean ± SD (B and D). ns: not significant; **P ≤0.005.