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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Mucosal Immunol. 2012 Mar 14;5(4):397–408. doi: 10.1038/mi.2012.17

Figure 6. MyD88 deletion does not modify mucus plugging, but promotes development of lymphoid aggregates in Scnn1b-Tg+ mice.

Figure 6

(a-c)Semi-quantitative histopathology scores for mucus plugs and mucous secretory cells (AB-PAS positive) in (a) neonatal trachea and (b-c) left lobe intrapulmonary main stem bronchus, at different time points. (d) Semi-quantitative histopathology scores for lymphoid aggregates (BALT). n= 6, 8, 3, 5 at 1–3 days (1–3d), n= 5, 6, 4, 8 at 5 days (5d), n= 13, 5, 10, 12 at 10 days (10d), n= 5, 4, 5, 9 at 4 weeks (4wk), and n= 8, 8, 11, 9 at 8 weeks (8wk) for MyD88+/−;Scnn1b-Tg-; MyD88−/−;Scnn1b-Tg-; MyD88+/−;Scnn1b-Tg+; and MyD88−/−;Scnn1b-Tg+ mice, respectively. ANOVA ** p<0.005, * p<0.05 vs. MyD88+/−;Scnn1b-Tg− mice. # p<0.05 vs. MyD88+/−;Scnn1b-Tg+ mice.