Table 6. Bivariate Analysis: Relationships between HIV Infection, Cytokines, Neurodevelopmental, and Sleep Factors in Adolescents with HIV Infection (Time 0, 6, 12, 18-Months Data).

Factors	Factor Components	Coefficient	P-Value*
	Intracellular cytokine-related factor
1	PMA CD4+ IL-10, PMA CD8+ IL-10, SEB CD4+ IL-10, SEB CD8+ IL-10, US CD4+ IL-10 and US CD8+ IL-10	−1.564	0.16
2	PMA CD4+ 69, PMA CD4+ TNF-α, PMA CD8+ 69 and PMA CD8+ TNF-α	−5.097	0.29
3	SEB CD4+ IFN-γ , SEB CD4+ TNF-α, SEB CD8+ IFN-γ and SEB CD8+ TNF-α	1.283	< 0.01
4	SEB CD8+ 69, US CD4+ 69 and US CD8+ 69	−0.618	0.61
5	US CD4+ IFN-γ, US CD8+ IFN-γ and US CD8+ TNF-α	0.777	0.10
6	PMA CD4+ IL-12, PMA CD8+ IL-12, SEB CD4+ IL-12 and SEB CD8+ IL-12	0.975	0.16
	Sleep actigraphy-related factors
1	Sleep Efficiency	1.351	0.41
2	Average of Number of Awakenings During Night and Total Time Awake at Night	−5.658	0.15
3	Difference of Total Time Asleep at Night and Sleep Latency	−16.008	0.56
4	Average of Total Time Asleep and Total Daytime Sleep	10.177	0.37
	Neurodevelopmental factors
1	BRIEF T BRI/MI/GEC & BASC Parent T Externalizing/Internalizing/Behavior/Adaptive	3.611	0.28
2	CHIPASAT B/C/D/E & DELIS-KAPLAN Motor Speed	−15.095	< 0.01
3	BRIEF Self T BRI/MI/GEC, BASC Self T Emotional	8.179	0.02
4	CMS Stories Immediate/Delayed/Recognition	−0.759	0.83
5	CPT T Omissions/Hit Reaction/Variability	2.260	0.56

^*Significant P values are bolded