To confirm that H2O2 production induces both the migration and invasion abilities of TSCC, UM2 cells and SOD2 shRNA-transfected UM1 cells (24 h) were treated with H2O2 for 24 h.
(A, B) The migration and invasion abilities of UM2 cells and SOD2 shRNA-transfected UM1 cells were significantly increased after treating with 100 μM H2O2 for 24 h. *: P< 0.05.
(C) The cellular proliferation rates of UM2 cells and SOD2 shRNA-transfected UM1 cells were significantly increased after treating with 100 μM H2O2 for 24 h. *: P< 0.05.