Table 1.

Median SIX2 and CITED1 expression by Western Blot and qRT-PCR stratified according to patient demographics, WT stage, histology, and treatment outcome.

Characteristic	N	Median SIX2 normalized to β-actin				Median CITED1 normalized to β-actin
		Protein	p	mRNA	p	Protein	p	mRNA	p
Age
0–23 months	11	0.84		1.10		0.48		.00178
24+ months	28	1.35	0.34	1.01	0.54	1.21	0.03	.00352	0.08
Gender
Male	19	1.21		1.19		0.91		.00311
Female	20	1.24	0.62	0.72	0.05	0.93	0.76	.00317	0.46
Stage
I	10	1.08		0.94		0.91		.00454
II	9	0.84		1.18		1.21		.00169
III	10	0.57		0.73		1.43		.00254
IV	10	1.66	0.48	1.28	0.38	0.63	0.86	.00344	0.43
Histology
Favorable	19	1.44		0.90		0.90		.00346
Unfavorable (anaplasia)	20	1.12	0.51	1.10	0.58	1.10	0.50	.00253	0.88
Outcome
Failure (relapse or death)	16	1.27		1.09		1.21		.00344
Non-failure	23	1.21	0.86	1.02	0.49	0.86	0.49	.00274	0.61