Table 1.

PLA2G7 SNPs included in the analyses.

rs_number	NPHS-II	UDACS	EPIC-Norfolk	THROMBO	Cyprus	Atherogene	LURIC	WH-II	HIFMECH	EAS	SAS	WTCCC*
†	n= 2725	n= 424	n= 4350	n= 529	n= 783	n= 1776	n= 3312	n= 5592	n= 1093	n= 1098	n= 1164	n= 4992
rs974670
HWE (P-value)	0.55	0.12		0.51	0.13	0.17
MAF	0.40	0.39	N/A	0.36	0.26	0.38	N/A	N/A	N/A	N/A	N/A	N/A
rs1805017
HWE (P-value)	0.71	0.69	0.06	0.37	0.51	0.60	0.70
MAF	0.27	0.24	0.25	0.29	0.31	0.22	0.26 ‡	N/A	N/A	N/A	N/A	N/A
rs9381475
HWE (P-value)	0.48	0.52	0.51	1.00	0.17	0.88
MAF	0.22	0.19	0.20	0.21	0.23	0.19	N/A	N/A	N/A	N/A	N/A	N/A
rs10948300
HWE (P-value)	0.80	1.00	0.59
MAF	0.22 §	0.17	0.20	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
rs2216465
HWE (P-value)	0.69	0.28	0.03
MAF	0.33 §	0.28	0.32	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
rs1421378
HWE (P-value)	1.00	0.68	0.04	0.10	0.20	0.92
MAF	0.4 §	0.38	0.38	0.41	0.48	0.36	N/A	N/A	N/A	N/A	N/A	N/A
rs1051931
HWE (P-value)	0.35	0.05	0.58	0.45	0.28	0.08	0.91	0.89	0.04	0.64	0.92	0.33
MAF	0.18	0.21	0.19	0.22	0.24	0.24	0.2 ‡	0.19	0.23 ||	0.19	0.19 #	0.2 **

All genotyping was done using TaqMan assays unless otherwise stated.

^*WTCCC-CHD: the information correspond to the SNP rs9472819, which is in complete LD (r²=1) with rs1051931;

^†Number of DNA samples available, although genotype numbers might differ;

^‡,RFLP/PCR;

^§Custom designed Illumina Bead Chip;

^||allele specific PCR ;

^#KASPar: see http://www.kbioscience.co.uk/genotyping/genotyping_chemistry.html,;

^**Affymetrix 500,