Table 2.
Summary of all determined perikarya- and nuclei volumes. Calculated mean ± SD volumes (μm3), diameter (d) (μm), number of cells (n) and frequency (%) of reconstructed perikarya and their corresponding nuclei of human cochleae are presented for pooled data of both cochleae as well as specimen-separated. Calculated volumes are additionally shown for apical-, middle- and basal turn of investigated specimen. Furthermore, evaluated values are presented for each population classified by the hierarchical cluster algorithm. The fist horizontal row (whole cochlea(e)) presents data calculated from all reconstructed cell bodies and their nuclei from specimen 1, specimen 2 and pooled data of both specimens respectively. The following horizontal rows (apical-, middle- and basal turn) show calculated data of analyzed SGCs according to their origin along the cochlea spiral
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean (μm3) | SD (μm3) | Mean (μm3) | SD (μm3) | n= | Frequ. (%) | Mean (μm3) | SD (μm3) | Mean (μm3) | SD (μm3) | n= | Frequ. (%) | Mean (μm3) | d (μm) | SD (μm3) | Mean (μm3) | SD (μm3) | n= | Frequ. (%) | ||
| Whole cochlea(e) | Population 1 | 1288 | 496 | 228.2 | 60.4 | 10 | 12.0 | 919.3 | 192 | 264 | 67 | 11 | 20 | 1154 | 13.01 | 429.7 | 247.9 | 64 | 24 | 17.4 |
| Population 2 | 3878 | 932.6 | 372.8 | 80 | 67 | 80.7 | 2441 | 461.3 | 290.2 | 53.4 | 13 | 23.6 | 3352 | 18.57 | 661.3 | 343.4 | 77.7 | 77 | 52.2 | |
| Population 3 | 6297 | 140.7 | 436.1 | 97.5 | 1 | 5.8 | 4393 | 620.5 | 359.9 | 89.9 | 20 | 36.4 | 5407 | 21.78 | 592.5 | 409.6 | 74.7 | 37 | 26.8 | |
| Population 4 | 8148 | 0 | 506.5 | 0 | 1 | 1.1 | 6636 | 826 | 418 | 60.6 | 11 | 20 | 7675 | 24.47 | 543.3 | 475.1 | 50.6 | 5 | 3.6 | |
| Apical turn | Population 1 | 1860 | 829.1 | 254.3 | 69.8 | 12 | 37.5 | 874.4 | 201.6 | 231.4 | 63.9 | 2 | 14.3 | 1162 | 13.04 | 472.6 | 236.3 | 69.1 | 5 | 19.5 |
| Population 2 | 4416 | 558.3 | 373.7 | 58.7 | 17 | 53 1 | 3616 | 551.2 | 256.5 | 34.2 | 5 | 35.7 | 3599 | 19.01 | 642.6 | 323.5 | 78.3 | 20 | 43.5 | |
| Population 3 | 6418 | 25 | 394.5 | 16.7 | 2 | 6.3 | 5844 | 453.8 | 370.7 | 59 | 5 | 35.7 | 5723 | 22.19 | 803.3 | 391 | 64.4 | 16 | 34.8 | |
| Population 4 | 8184 | 0 | 506.5 | 0 | 1 | 3.1 | 7142 | 286.8 | 508.4 | 44 | 2 | 14.3 | 8148 | 24.97 | 0 | 506.5 | 0 | 1 | 2.2 | |
| Middle turn | Population 1 | 970.9 | 0 | 196.5 | 0 | 1 | 4.2 | 2294 | 359.7 | 281 | 55.8 | 8 | 38.1 | 2049 | 15.76 | 450.7 | 258.3 | 53.1 | 10 | 21.7 |
| Population 2 | 2211 | 280.6 | 251.8 | 19.8 | 3 | 12.5 | 3621 | 222.6 | 315.4 | 108.6 | 4 | 19 | 3376 | 18.61 | 385.1 | 337.5 | 64.5 | 22 | 47.8 | |
| Population 3 | 3513 | 480.8 | 343.4 | 54 | 17 | 70.8 | 4683 | 338.1 | 402.5 | 74.1 | 8 | 38.1 | 4739 | 20.84 | 352.6 | 383 | 68.9 | 13 | 28 3 | |
| Population 4 | 5078 | 234.4 | 375 | 52.6 | 3 | 12.5 | 6293 | 0 | 364.7 | 0 | 1 | 4.8 | 6293 | 22.91 | 0 | 364.7 | 0 | 1 | 2.2 | |
| Basal turn | Population 1 | 852.9 | 0 | 201.9 | 0 | 1 | 3.7 | 1012 | 322.5 | 275.9 | 66.8 | 10 | 50 | 1025 | 12.51 | 298.7 | 274.8 | 64.7 | 11 | 23.9 |
| Population 2 | 2942 | 438.6 | 402.4 | 81.8 | 13 | 48.2 | 3036 | 529.9 | 361.5 | 58.3 | 3 | 15 | 3035 | 17.96 | 446.5 | 388.9 | 71.2 | 16 | 34.8 | |
| Population 3 | 4822 | 535.8 | 456 | 94.6 | 10 | 37 | 5519 | 688.9 | 413.5 | 39.9 | 5 | 25 | 5250 | 21.56 | 750.4 | 452.9 | 84.5 | 17 | 37 | |
| Population 4 | 6227 | 132.7 | 507.9 | 93.2 | 3 | 11.1 | 7970 | 363.9 | 425.7 | 12.5 | 2 | 10 | 7970 | 24.78 | 363.9 | 425.7 | 12.5 | 2 | 4.3 | |