Figure 4.

T-regulation of BChE activity in male mdx sera. BChE activities were measured colorimetrically with BTCh as substrate in sera of intact, castrated, castrated with T-replacement, and sham operated wt and mdx □ mice, (as in Figure 3A). Values, mean ± SEM for samples taken from 4 to 8 mice per group (sham group, n = 3). ^*p < 0.001 between BChE levels in castrated wt and in intact, T-treated, and sham mice sera (of either wt or mdx strains). ^**p < 0.05 (detailed in 3) between BChE levels in castrated mdx and in intact, T-treated, and sham mdx mice sera. #Significant difference between BChE level in mdx and wt in all the experimental groups (p-values are listed in 2). The dashed black and red lines indicate BChE levels in agonadal and gonadal wt sera, respectively.