Figure 2. Cytokine secretion from HBs and CS peptide stimulated PBMCs in vaccinees and controls.
PBMCs were cultured in growth medium alone (GM), with HBs or CS peptides for 24 h and culture supernatants from 38 RTS,S/AS01E vaccinees and 54 controls were collected and analyzed by Luminex bead array for (A) IFN-γ, (B) IL-2 and (C) IL-10. The horizontal line within each box represents the median; the top and bottom of each box represent the 25th and 75th percentiles, respectively, and the whiskers represent the upper and lower limits of values within 1.5 times the interquartile range. Circles denote outliers. P values are derived from paired Mann Whitney tests.