Table I.
Baseline characteristics of subjects
RTS,S/AS01E n= 81 |
Control n=104 |
||
---|---|---|---|
Age (months)* | 11.7 (± 0.4) | 11.9 (± 0.3) | |
Sex (% Female) | 52.5 | 48.1 | |
[Hb] (g/dL)* | 10.6 (± 1.1) | 10.7 (± 1.0) | |
WBC(10−9/L)* | 9.9 (± 3.3) | 9.6 (± 3.4) | |
P. falciparum positive
(n) ** |
0 | 1 | |
Anti-
HBSAg Ab titre (U/ml) *** |
Pre-vacc | 148 (43-382) | 258 (87-643) |
Month 3 | 48489 (4708 -132314) | 213 (77-475)† | |
Month 12 | 9357 (3937-16269) | 148 (33-436)† | |
Anti-CS
Ab titre (U/ml) *** |
Pre-vacc | 0.25 (0.25 – 0.25) | 0.25 (0.25 – 0.25) |
Month 3 | 506 (314-814) | 0.25 (0.25 – 0.25)† | |
Month 12 | 37 (23-58) | 0.25 (0.25 – 0.25)† |
Mean (SD)
Microscopic analysis of Giemsa-stained blood smears
Median values plus interquartile ranges (25%-75%)
Titres are significantly higher in RTS,S/AS01 vaccinees than controls (p ≤ 0.01)