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. Author manuscript; available in PMC: 2012 Nov 15.
Published in final edited form as: J Immunol. 2012 Apr 13;188(10):5054–5062. doi: 10.4049/jimmunol.1102710

Table I.

Baseline characteristics of subjects

RTS,S/AS01E
n= 81
Control
n=104
Age (months)* 11.7 (± 0.4) 11.9 (± 0.3)
Sex (% Female) 52.5 48.1
[Hb] (g/dL)* 10.6 (± 1.1) 10.7 (± 1.0)
WBC(10−9/L)* 9.9 (± 3.3) 9.6 (± 3.4)
P. falciparum positive
(n) **
0 1
Anti-
HBSAg
Ab titre
(U/ml) ***
Pre-vacc 148 (43-382) 258 (87-643)
Month 3 48489 (4708 -132314) 213 (77-475)
Month 12 9357 (3937-16269) 148 (33-436)
Anti-CS
Ab titre
(U/ml) ***
Pre-vacc 0.25 (0.25 – 0.25) 0.25 (0.25 – 0.25)
Month 3 506 (314-814) 0.25 (0.25 – 0.25)
Month 12 37 (23-58) 0.25 (0.25 – 0.25)
*

Mean (SD)

**

Microscopic analysis of Giemsa-stained blood smears

***

Median values plus interquartile ranges (25%-75%)

Titres are significantly higher in RTS,S/AS01 vaccinees than controls (p ≤ 0.01)