Table III.
Proportion of individuals with a secreted cytokine response1 to HBs or CS peptides.
| Antigen | Group | IFN-γ | IL-2 | IL-10 | |
|---|---|---|---|---|---|
| HBs |
RTS,S/AS01E N = 38 |
n (%) |
20 (52.6) |
37 (97.4) |
18 (47.4) |
|
Control N = 54 |
9 (16.7) |
32 (59.3) |
8 (14.8) |
||
| p | 0.0005 | <0.0001 | 0.0009 | ||
| CS |
RTS,S/AS01E N = 38 |
n (%) |
6 (15.8) |
26 (68.4) |
4 (10.5) |
|
Control N = 54 |
13 (24.1) |
3 (5.6) |
3 (5.6) |
||
| p | 0.44 | <0.0001 | 0.44 |
1
Responders are defined as those with a peptide-specific cytokine response greater than or equal to the mean + 2SD of their own negative control (GM) values