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. Author manuscript; available in PMC: 2012 Nov 10.
Published in final edited form as: Nature. 2012 May 10;485(7397):251–255. doi: 10.1038/nature10992

Fig. 1. TAC-induced cardiomyopathy in Dnase2a−/−mice.

Fig. 1

a, Survival ratio after TAC (n = 7 – 14/group). b – g, 10 days after TAC. b, Gross appearance of hearts. Scale bar, 2 mm. c, Echocardiography. Scale bars, 0.2 sec and 5 mm. Echocardiographic (d) and physiological (e) parameters (n = 7 – 13/group). LVIDd and LVIDs indicate end-diastolic and end-systolic left ventricle (LV) internal dimension, respectively; LVFS, LV fractional shortening; HW/BW, heart/body weight. Hematoxylin-eosin-stained (f) and Azan-Mallory-stained (g) heart sections. Scale bar, 100 μm. Data are mean ± s.e.m. *P < 0.05 versus all other groups, †P < 0.05 versus sham-operated controls.