Fig. 2.
XE-991 (40 μM)-sensitive M-current in POMC neurons is not affected by fasting. A: currents were recorded under control conditions and after 10 min of perfusion of 40 μM XE-991 in the presence of 0.5 μM TTX in fed and 24-h-fasted male mice. B: XE-991 (XE) depolarized POMC neurons significantly in fed and fasted male mice. RMP, resting membrane potential. *P < 0.05; **P < 0.01 (by Student's t-test).