Table 4.
CON | IUGR | PNGR | IPGR | ||
---|---|---|---|---|---|
HR, (beats/min) | PreHx | 410 ± 32 | 393 ± 38 | 432 ± 49 | 417 ± 42 |
PostAc. Hx | 402 ± 48 | 402 ± 38 | 455 ± 38 | 471 ± 28* | |
PostChr. Hx | 408 ± 27 | 397 ± 44 | 419 ± 28 | 389 ± 15 | |
VST, mm | PreHx | 1.4 ± 0.2 | 1.5 ± 0.1 | 1.3 ± 0.1 | 1.3 ± 0.2 |
PostAc. Hx | 1.3 ± 0.1 | 1.4 ± 0.1 | 1.3 ± 0.2 | 1.4 ± 0.1 | |
PostChr. Hx | 1.3 ± 0.05 | 1.6 ± 0.3 | 1.4 ± 0.2 | 1.3 ± 0.2 | |
PWT, mm | PreHx | 1.4 ± 0.1 | 1.5 ± 0.1 | 1.3 ± 0.1‡ | 1.4 ± 0.1 |
PostAc. Hx | 1.5 ± 0.1 | 1.4 ± 0.1 | 1.3 ± 0.2 | 1.4 ± 0.1 | |
PostChr. Hx | 1.4 ± 0.2 | 1.5 ± 0.2 | 1.3 ± 0.2 | 1.3 ± 0.1 | |
ESD, mm | PreHx | 4.3 ± 0.6 | 4 ± 0.5 | 4 ± 0.4‡ | 4 ± 0.4 |
PostAc. Hx | 4.4 ± 0.6 | 4.3 ± 0.4 | 4.2 ± 0.4 | 3.4 ± 0.4* | |
PostChr. Hx | 4.7 ± 0.2 | 4 ± 0.6 | 4 ± 0.3 | 4.5 ± 0.5* | |
EDD, mm | PreHx | 7.5 ± 0.6 | 7.2 ± 0.3 | 7.3 ± 0.5 | 6.7 ± 0.4 |
PostAc. Hx | 7.3 ± 0.4 | 7.3 ± 0.7 | 7 ± 0.3 | 6.4 ± 0.4 | |
PostChr. Hx | 7.3 ± 0.4 | 6.7 ± 0.7* | 6.8 ± 0.3 | 6.9 ± 0.3 | |
VCF, cir/s | PreHx | 6.7 ± 0.7 | 6.7 ± 1.3 | 7.2 ± 0.8 | 6.7 ± 1 |
PostAc. Hx | 6.2 ± 1.3 | 6.4 ± 0.5 | 6.8 ± 0.9 | 7.6 ± 0.7 | |
PostChr. Hx | 5 ± 0.8 | 6.5 ± 1.3 | 6.8 ± 0.8 | 5.1 ± 0.8* | |
LVM, mg | PreHx | 705 ± 131 | 714 ± 73 | 622 ± 93 | 573 ± 100‡ |
PostAc. Hx | 678 ± 102 | 677 ± 115 | 608 ± 114 | 544 ± 88 | |
PostChr. Hx | 662 ± 44 | 662 ± 145 | 594 ± 69 | 571 ± 103 | |
LVM/BW | PreHx | 3.3 ± 0.5 | 3.1 ± 0.4 | 3.2 ± 0.6 | 3.5 ± 0.5 |
PostAc. Hx | 3.5 ± 0.5 | 3.1 ± 0.5 | 3.4 ± 0.6 | 3.6 ± 0.5 | |
PostChr. Hx | 2.8 ± 0.3* | 3 ± 0.6 | 3 ± 0.1 | 3 ± 0.5* |
Heart rate (HR), ventricular septal thickness (VST), posterior wall thickness (PWT), end systolic dimension (ESD), end diastolic dimension (EDD), velocity of circumferential fiber (VCF), left ventricular mass and left ventricular mass (LVM) to body weight (BW) ratio. Echocardiographic assessments at baseline (prehypoxia; preHx), after 2 days of hypoxia (postacute; postAc. Hx ) and after 7 days of hypoxia (postchronic; postChr. Hx) in 4 experimental groups. Values are means ± SE; n = 6 per treatment and per group. Fisher's PLSD
P < 0.05 vs. prehypoxia,
P < 0.05 vs. CON prehypoxia.