Colonic miRNA expressions are downregulated in DSS-treated WT mice. Expression of colonic miRNA 23a, 23b, 200c, 92a, and 375 were downregulated in DSS-treated WT compared with WT control mice, whereas their expression in Tg mice is nonsignificant under the same conditions as shown by real-time RT-PCR. Values represent means ± SE of n = 6/group. *P < 0.05, **P < 0.005, and ***P < 0.001.