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. 2012 Apr 12;302(11):G1282–G1291. doi: 10.1152/ajpgi.00401.2011

Fig. 7.

Fig. 7.

A: tight junction-associated protein 1 (Tjap1) is regulated by colonic miRNA 132 in DSS-treated Tg mice. mRNA and protein expression of Tjap1 (molecular weight 61 kDa), a potential target of colonic miRNA 132, is decreased in DSS-treated Tg mice colon compared with Tg control mice, whereas its expression remains unchanged or nonsignificant in WT DSS-treated and WT control mice. B: CD163 is regulated by colonic miRNA 23a and 23b in DSS-treated WT mice. mRNA and protein expression of CD163 (molecular weight 130 kDa), a potential target of colonic miRNA 23a and 23b, is increased in colonic tissue of DSS-treated WT mice compared with WT control mice, whereas its expression remains low in DSS-treated and control Tg mice. Values represent means ± SE of n = 6/group. *P < 0.05.