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Rat papillary cell migration across filters. Cells seeded on collagen IV-coated filters migrated across the filters in the presence of a gradient of stromal cell-derived factor-1 (SDF-1) but failed to migrate to a gradient of PDGF. SDF-1-induced migration required the presence of collagen IV since SDF-1 was ineffective in uncoated filters or filters coated with collagen I. *P < 0.01; n = 4–6 individual experiments for each ligand.
