Table 2.
Results from the volumetric analysis, cortical thickness, and surface area for Leu607Phe genotypes.
| Phe carriers (standard error) | LeuLeu homozygotes (standard error) | t-Value (p-value) | |
|---|---|---|---|
| STRIATUM VOLUME (mm3) | |||
| Left striatum | 10,240 (374) | 9,043 (124) | 2.48 (0.017)* |
| Right striatum | 10,167 (268) | 8,995 (121) | 2.49 (0.016)* |
| BRAIN VOLUME (mm3) | |||
| Whole brain | 1,426,783 (33,652) | 1,345,396 (15,275) | 1.63 (0.10) |
| Left hemisphere | 604,272 (15,570) | 559,396 (7,094) | 2.80 (0.0074) |
| Right hemisphere | 541,537 (14,449) | 488,030 (6,583) | 1.71 (0.093) |
| CORTICAL SURFACE AREA (mm2) | |||
| Left parietal lobe | 20,434 (542) | 19,028 (246) | 1.82 (0.075) |
| Left occipital lobe | 11,891 (416) | 10,945 (190) | 1.71 (0.094) |
| Left parasplenium | 642 (38) | 550 (17) | 1.91 (0.062) |
| Left insula | 1,645 (57) | 1,524 (26) | 1.67 (0.10) |
| Right occipital lobe | 12,350 (383) | 11,110 (174) | 2.56 (0.014) |
| Right parasplenium | 569 (32) | 502 (15) | 1.68 (0.099) |
*Total brain volume included in the linear model.