Table 2. Trends in resistance rate of Klebsiella pneumoniae to antibiotics, 2006 to 2010.
Antibiotics | 2006 | 2007 | 2008 | 2009 | 2010 | R2 | P | 95% CI | Trend |
---|---|---|---|---|---|---|---|---|---|
Cefazolin |
62.3 |
63.5 |
58.8 |
54.5 |
74.1 |
0.10 |
0.60 |
–6.59-9.51 |
Stable |
Cefuroxime |
54.0 |
69.9 |
63.3 |
61.7 |
74.0 |
0.42 |
0.23 |
–3.64-10.00 |
Stable |
Ceftazidime |
28.6 |
43.7 |
58.8 |
55.7 |
72.1 |
0.91 |
0.01 |
4.09-15.71 |
Increasing |
Ceftriaxone |
40.6 |
48.6 |
59.4 |
59.7 |
72.2 |
0.95 |
<0.01 |
4.38-10.48 |
Increasing |
Cefepime |
30.4 |
63.1 |
60.1 |
56.6 |
72.5 |
0.61 |
0.12 |
–3.70-19.24 |
Stable |
Aztreonam |
35.9 |
65.2 |
60.1 |
56.7 |
73.4 |
0.56 |
0.14 |
–4.08-17.38 |
Stable |
Imipenem |
2.3 |
6.1 |
7.5 |
9.5 |
25.2 |
0.78 |
0.05 |
0 .06-9.78 |
Increasing |
Meropenem |
1.0 |
4.1 |
6.8 |
10.9 |
29.0 |
0.81 |
0.04 |
0 .68-1.88 |
Increasing |
Amoxicillin/clavulanate |
38.2 |
41.5 |
36.1 |
35.9 |
54.5 |
0.30 |
0.34 |
–4.81-10.21 |
Stable |
Ampicillin/sulbactam |
49.5 |
53.3 |
43.8 |
50.0 |
66.7 |
0.33 |
0.31 |
–5.03-11.25 |
Stable |
Piperacillin/tazobactam |
25.0 |
35.1 |
20.2 |
24.3 |
47.0 |
0.24 |
0.41 |
–7.67-14.31 |
Stable |
Cefoperazone/sulbactam |
15.0 |
10.3 |
10.6 |
20.0 |
38.2 |
0.59 |
0.13 |
–2.95-14.17 |
Stable |
Amoxicillin |
24.2 |
25.2 |
23.5 |
18.6 |
41.2 |
0.26 |
0.39 |
–5.87-11.35 |
Stable |
Levofloxacin | 40.6 | 43.2 | 31.3 | 32.6 | 52.6 | 0.06 | 0.69 | –8.41-11.09 | Stable |