Table 4. Trends in resistance rate of Citrobacter to antibiotics, 2006 to 2010.
| Antibiotics | 2006 | 2007 | 2008 | 2009 | 2010 | R2 | P | 95% CI | Trend |
|---|---|---|---|---|---|---|---|---|---|
| Cefuroxime |
56.7 |
72.4 |
77.2 |
69.0 |
95.0 |
0.69 |
0.08 |
–1.72-16.36 |
Stable |
| Ceftazidime |
28.6 |
40.0 |
56.6 |
47.1 |
80.0 |
0.80 |
0.04 |
0.91-1.07 |
Increasing |
| Ceftriaxone |
37.5 |
71.4 |
73.4 |
75.0 |
95.0 |
0.82 |
0.03 |
1.59-22.12 |
Increasing |
| Cefepime |
20.0 |
43.3 |
42.9 |
47.1 |
33.3 |
0.19 |
0.46 |
–8.38-14.46 |
Stable |
| Aztreonam |
31.4 |
43.3 |
58.5 |
50.0 |
63.2 |
0.78 |
0.05 |
0.14-3.92 |
Increasing |
| Imipenem |
20.0 |
11.1 |
15.8 |
6.9 |
23.8 |
0.00 |
0.93 |
–10.87-11.55 |
Stable |
| Meropenem |
10.0 |
3.4 |
1.8 |
9.1 |
31.6 |
0.42 |
0.24 |
–5.70-15.48 |
Stable |
| Amoxicillin/clavulanate |
77.1 |
85.7 |
85.5 |
78.8 |
90.5 |
0.33 |
0.31 |
–3.25-7.23 |
Stable |
| Ampicillin/sulbactam |
61.9 |
63.0 |
69.4 |
75.0 |
82.0 |
0.96 |
<0.01 |
3.28-7.16 |
Increasing |
| Piperacillin/tazobactam |
15.2 |
14.3 |
25.0 |
41.2 |
52.9 |
0.92 |
0.01 |
4.61-15.85 |
Increasing |
| Cefoperazone/sulbactam |
11.4 |
10.3 |
10.5 |
42.9 |
19.0 |
0.29 |
0.35 |
–8.82-18.38 |
Stable |
| Amoxicillin |
26.5 |
32.1 |
44.6 |
25.8 |
33.3 |
0.02 |
0.81 |
–7.94- 9.40 |
Stable |
| Levofloxacin | 20.6 | 44.8 | 60.6 | 64.3 | 65.4 | 0.83 | 0.03 | 1.75-20.07 | Increasing |