. Author manuscript; available in PMC: 2012 Jun 19.

Published in final edited form as: J Anal At Spectrom. 2009 Jan;24(1):51–61. doi: 10.1039/B810481F

Table 6.

Cellular amounts of Ru and Pt after exposure to equicytotoxic concentrations, determined with the developed protocol. Average cellular Ru (KP1019, 50 μM) and Pt (cisplatin, 3 μM during exposure) in SW480 cells expressed in fg cell⁻¹ and ng mg⁻¹ protein, determined in n independent experiments. The average cell number during drug exposure and the protein concentration per cell were determined and used as quality control parameters for uptake experiments

	Ru	Pt
fg per cell	31 ± 4 (n = 11)	0.9 ± 0.3 (n = 7)
ng per mg protein	171 ± 7 (n = 5)	5 ± 1 (n = 5)
ng protein per cell	0.19 ± 0.02 (n = 7)
Average cell number	3.9 ± 0.75 × 10⁵ (n = 11)