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. 2012 Apr 13;302(12):H2583–H2591. doi: 10.1152/ajpheart.01170.2011

Table 2.

Hemodynamic changes after 1 h of RAP

Parameters Baseline NSR NSR Post-RAP P Value* NSR 1 h Post-RAP P Value* P Value‡
LA active emptying fraction†, % 17.6 ± 7.5 11.7 ± 3.7 <0.001 10.2 ± 4.3 <0.001 0.465
RA active emptying fraction†, % 11.4 ± 4.8 10.7 ± 4.0 0.499 10.7 ± 4.1 0.309 0.751
LA ESPVR-slope, mmHg/ml 1.64 ± 0.69 1.59 ± 0.98 0.619 1.14 ± 0.63 0.306 0.561
LA ESPVR-intercept V10, ml 24.3 ± 4.9 28.1 ± 5.2 0.005 28.7 ± 8.4 0.012 0.841
    r2 0.86 ± 0.13 0.88 ± 0.06 0.25 0.92 ± 0.04 0.125 0.605
RA ESPVR-slope, mmHg/ml 1.07 ± 0.43 1.20 ± 0.41 0.455 1.35 ± 0.42 0.122 0.433
RA ESPVR-intercept V10, ml 33.2 ± 6.3 33.5 ± 6.3 0.139 37.5 ± 5.6 0.006 0.136
    r2 0.83 ± 0.09 0.84 ± 0.13 0.716 0.88 ± 0.09 0.318 0.196
Maximum LA ΔP/Δt/P, s−1 12.3 ± 7.1 9.6 ± 4.0 0.026 10.5 ± 3.9 0.122 0.409
Maximum RA ΔP/Δt/P, s−1 12.9 ± 3.6 11.6 ± 2.9 0.157 10.9 ± 2.8 0.062 0.663
LA EDPVR-slope, mmHg/ml 1.03 ± 0.54 1.53 ± 0.96 0.120 1.12 ± 0.71 0.298 0.615
    r2 0.88 ± 0.07 0.90 ± 0.09 0.980 0.88 ± 0.08 0.967 0.986
LA compliance, ml/mmHg 10.6 ± 6.0 9.0 ± 5.2 0.814 12.6 ± 6.2 0.213 0.145
LA EDPVR-intercept V10, ml 27.8 ± 5.6 32.3 ± 6.1 0.011 31.9 ± 8.9 0.083 0.363
RA EDPVR-slope, mmHg/ml 0.98 ± 0.19 1.25 ± 0.43 0.261 1.16 ± 0.49 0.391 0.817
    r2 0.79 ± 0.14 0.87 ± 0.06 0.214 0.89 ± 0.08 0.082 0.537
RA compliance, ml/mmHg 8.2 ± 2.6 8.5 ± 4.5 0.662 9.6 ± 3.6 0.458 0.741
RA EDPVR-intercept V10, ml 35.2 ± 6.0 38.2 ± 7.8 0.045 38.8 ± 5.9 0.004 0.188
LA PED/VED, mmHg/ml 0.53 ± 0.14 0.51 ± 0.10 0.361 0.46 ± 0.12 0.039 0.247
RA PED/VED, mmHg/ml 0.35 ± 0.10 0.40 ± 0.11 0.020 0.41 ± 0.12 0.013 0.921
RA conduit function, %RA inflow 49 ± 24 57 ± 12 0.209 58 ± 16 0.165 0.889
Early conduit function, % 36 ± 20 39 ± 14 0.523 40 ± 23 0.466 0.929
Late conduit function, % 14 ± 15 18 ± 13 0.405 18 ± 16 0.325 0.880

Values are means ± SD. ESPVR, end-systolic pressure-volume relation; V10, end-systolic volume required to generate an atrial end-systolic pressure of 10 mmHg; r2, correlation coefficient; EDPVR, end-diastolic pressure volume relation; PED/VED, ratio of pressure to volume at end-diastole.

†

Calculated from conductance;

*

vs. baseline; and

‡

NSR post-RAP vs. NSR 1 h post-RAP.