Table 2.

Hemodilution with low-viscosity 70-kDa dextran, high-viscosity 500-kDa dextran, and PEG-Alb

	Control*	70-kDa Dextran*	500-kDa Dextran†	PEG-Alb*
Hct, %	49.3 ± 1.8	11.1 ± 0.9	11.0 ± 0.6	11.2 ± 0.7
Mean arterial pressure, mmHg	103 ± 6	64 ± 8	87 ± 6	79 ± 7
Heart rate, beats/min	414 ± 35	418 ± 41	453 ± 38	460 ± 31
Cardiac output, ml/min	17.8 ± 1.6	14.2 ± 1.9	19.6 ± 3.5	24.2 ± 1.6
Base-excess, mmol/l	3.2 ± 1.5	−4.6 ± 2.6	0.8 ± 1.6	1.3 ± 1.4
Plasma viscosity, cP‡	1.2 ± 0.1	1.4 ± 0.2	2.2 ± 0.2	1.3 ± 0.1
Blood viscosity, cP‡	4.1 ± 0.4	2.1 ± 0.2	2.8 ± 0.2	1.8 ± 0.1
Peripheral resistance§	1.00	0.78	0.76	0.57
Arterial blood pH	7.35 ± 0.03	7.32 ± 0.09	7.35 ± 0.06	7.36 ± 0.04

^*Data from Ref. 13.

^†Data from Ref. 10.

^‡Viscosity measured in a Brookfield cone-and-plate viscometer at 200 s⁻¹.

^§Ratio of mean arterial blood pressure and cardiac output normalized relative to baseline.