Fig. 2.
Inhibition of the RhoA/Rho kinase signal does not reduce uterine and mesenteric contractile responses to U-46619 in pregnant rats. A–D: effects of the Rho kinase inhibitor Y-27632 (10−6 M) on cumulative concentration-response curves to U-46619 (10−9–10−5 M) in virgin uterine (A; n = 11), virgin mesenteric (B; n = 11), pregnant uterine (C; n = 12), and pregnant mesenteric (D; n = 12) arteries. Data are means ± SE. *P < 0.05 vs. U-46619 alone as determined by two-way repeated-measures ANOVA.