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A: mean suppression of rNST-evoked inward current by Y1 receptor agonist d-arg-25-NPY at 3 concentrations. B: suppression at 0.5 μM is statistically significant (paired t-test). The suppression recovered almost completely with washout. C: example of the increase in the paired-pulse ratio. D: average increase in paired-pulse ratio was statistically significant for the 12 out of 18 neurons that showed suppression with d-arg-25-NPY.
