Table 1.
Hemodynamic, morphological, and exercise performance data in sham and CHF rats following exercise training
| Sham + Sed (n = 42) | Sham + ExT (n = 40) | CHF + Sed (n = 42) | CHF + ExT (n = 43) | |
|---|---|---|---|---|
| Body weight, g | 462 ± 9 | 410 ± 6* | 485 ± 9 | 429 ± 8# |
| Heart weight, mg | 1,511 ± 20 | 1,515 ± 22 | 2,540 ± 30* | 2,469 ± 31* |
| HW/BW, mg/g | 3.3 ± 0.1 | 3.7 ± 0.1 | 5.2 ± 0.1* | 5.7 ± 0.1* |
| WLW/BW, mg/g | 5.0 ± 0.3 | 5.1 ± 0.3 | 9.5 ± 0.5* | 9.0 ± 0.5* |
| MAP, mmHg | 109.6 ± 2.5 | 104.2 ± 2.5 | 90.5 ± 2.0* | 99.5 ± 2.2 |
| HR, beats/min | 363.5 ± 7.5 | 344.3 ± 6.9 | 379.1 ± 6.8 | 367.1 ± 6.9 |
| LVEDP, mmHg | 0.3 ± 0.4 | −0.2 ± 0.7 | 19.1 ± 1.6* | 17.3 ± 1.5* |
| EF, % | 76.1 ± 0.8 | 78.0 ± 0.8 | 37.9 ± 1.7* | 39.5 ± 1.6* |
| FS, % | 45.4 ± 0.7 | 46.1 ± 0.7 | 23.1 ± 1.0* | 24.2 ± 1.0* |
| Infarct size, % | 0 | 0 | 42.7 ± 1.8* | 40.2 ± 2.0* |
| CS, μmol•g−1•min−1 | 16.6 ± 1.0 | 25.1 ± 1.2* | 9.2 ± 0.8* | 17.2 ± 1.0# |
| Exercise performance, min | 3.4 ± 0.1 | 7.1 ± 0.1* | 1.2 ± 0.1* | 3.1 ± 0.1# |
Values are means ± SE. Sed, sedentary; ExT, excerise trained;, CHF, chronic heart failure; BW, body weight; HW, heart weight; WLW, wet lung weight; MAP, mean arterial pressure; LVEDP, left ventricle end-diastolic pressure; EF, ejection fraction; FS, fractional shortening; CS, citrate synthase activity.
*
P < 0.05 vs. sham+Sed.
#
P < 0.05 vs. CHF+Sed.