Figure 4. Upregulation of PGC-1α expression in the young and aged rat cortex during chronic hypoxic exposure.
A, Representative Western blot analysis of PGC-1α, following 10 days of hypoxic exposure in the young and old F344 rats. Data are representative of at least 3 experiments. B, Optical density ratios of PGC-1α normalized to β-actin before and after hypoxic exposure as a function of age. Each value represents the mean +/− SD from at least three rats. *p < 0.05 compared with control (non-hypoxic) cortical samples.