Table 3.
List of colon tissue-specific proteins which have not been previously studied as serum cancer or benign disease biomarkers
| Gene | Protein name | Proteome identified in: | |
|---|---|---|---|
| CM proteome from colon cancer cell lines | Non-colon proteome | ||
| CEACAM7 | Carcinoembryonic antigen-related cell adhesion molecule 7 | √ CM proteome from Hep 3B [52]; pancreatic juice proteome [33] | |
| CLCA1 | Chloride channel accessory 1 | √ Normal, Down Syndrome amniotic fluid [22,23] | |
| GPA33 | Glycoprotein A33 | √ LS174Ta, LS180a, Colo205 [52] | |
| LEFTY1 | Left-right determination factor 1 | ||
| ZG16 | Zymogen granule protein 16 homolog (rat) | √ CM proteome from Hep 3B [52] | |
aCM proteome of colon cancer cell lines (GS Karagiannis et al., unpublished work). CM: conditioned media.