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. 2012 Jun 19;7(6):e39296. doi: 10.1371/journal.pone.0039296

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Treatment duration and timing of follow-up sputum smear examinations for new and previously-treated cases of tuberculosis, highlighting the timing of the follow-up mid-continuation phase sputum smear examination. The initial two-three month intensive phase (light blue bars) is followed by a follow-up sputum smear examination (pink bars). If the follow-up sputum smear examination is positive, an additional 1-month extended-intensive phase treatment is given (dark blue bar), with additional follow-up sputum smear examination. After the intensive phase (or extended intensive phase), the continuation phase of treatment (grey bars) is immediately begin. After two months of continuation phase (i.e. between months 4 and 6), the mid-continuation phase (mid-CP) follow-up sputum smear examination is done (red bars, circled with dotted line). At the end of the continuation phase, a final follow-up sputum smear examination is done.