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. 2012 Jun 19;7(6):e39296. doi: 10.1371/journal.pone.0039296

Table 1. Impact of various policy options with regard to mid-CP follow-up on the number of cases of tuberculosis treatment failures detected early1 and laboratory workload.

Policy Options for mid-CP follow-up Total patients tested (%)2 Cases of TreatmentFailure detected early1(Gain/Loss)3 Number needed to testto detect one case oftreatment failure early1
Continue as per present guideline 10055 (100) 323 31
Discontinue in new end-IP negative cases 3154 (31) 323 10
Discontinue in all new cases 2040 (20) 206 (−117) 10
Discontinue in all end-IP negative cases 1531 (15) 214 (−109) 7
Schedule mid-CP follow-up to 5th month for all cases 10055 (100) 421 (+98) 24
1

Detected as a case of treatment failure around two-three months earlier than if detected at the end of the treatment.

2

Percentage calculated by taking follow-up required under present policy as denominator.

3

Gain/Loss in absolute numbers indicated respectively by a positive or a negative sign; CP-Continuation Phase of TB treatment.