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. 2012 Jun 19;7(6):e39461. doi: 10.1371/journal.pone.0039461

Figure 1. Metabolic syndrome network visualizing cardiovascular risk factor burden, clustering, and flow of its components between baseline and five-year follow-up.

Figure 1

“Healthy”, no prevalent metabolic syndrome component; “Obesity”, waist circumference: men >94 cm, women > 80 cm; “Glucose”, elevated non-fasting glucose: ≥8.0 mmol/l or antidiabetic treatment (anatomic-therapeutical-chemical [ATC] codes A10A, A10B); “HDL”, decreased high-density lipoprotein cholesterol: men <1.0 mmol/l, women <1.3 mmol/l, or lipid-lowering treatment (ATC C10AB, A10AD); “TG”, elevated non-fasting triglycerides: ≥2.3 mmol/l or lipid-lowering treatment (ATC C10AB, A10AD); “BP”, elevated blood pressure: ≥130/85 mmHg or antihypertensive drug treatment. The size of a node is proportional to the number of individuals in the risk factor state that the node represents. The inner circle of a node denotes individuals remaining in that risk factor state between baseline and follow-up, whereas the outer circle of a node denotes individuals moving between risk factor states. The networks' flow between baseline and follow-up is shown for the 39 most important links (13% of all 301 links), representing 84.5% of total flow. The weight and colour shade of a link represent the number of individuals moving between the two states that the link connects.