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. 2012 Jun 19;7(6):e39461. doi: 10.1371/journal.pone.0039461

Table 3. Risk factor flow for the 39 most important links.

Rank Risk factor cluster from baseline to follow-up Change in number of MetS components Total flow (%)
1 Healthy Healthy  =  8.2
2 Obesity & BP Obesity & BP  =  6.9
3 Obesity & BP Obesity, HDL & BP + 6.3
4 BP BP  =  4.6
5 Healthy HDL  =  3.5
6 Obesity, HDL, TG, BP Obesity, HDL, TG & BP  =  2.9
7 Obesity, TG & BP Obesity, HDL, TG & BP + 2.6
8 Obesity, HDL & BP Obesity, HDL & BP  =  2.5
9 BP Obesity & BP + 2.2
10 Healthy BP  =  2.1
11 Obesity & BP Obesity, HDL, TG & BP + 1.9
12 BP HDL & BP + 1.8
13 BP Obesity, HDL & BP + 1.8
14 BP Healthy  =  1.7
15 Obesity Obesity & HDL + 1.7
16 Healthy Obesity  =  1.6
17 Obesity, TG & BP Obesity, HDL & BP  =  1.6
18 Obesity Obesity  =  1.5
19 Obesity, TG & BP Obesity & BP 1.5
20 Obesity, HDL, TG & BP Obesity, HDL & BP 1.2
21 HDL HDL  =  1.1
22 Healthy Obesity & HDL + 0.9
23 Obesity Obesity & BP + 0.9
24 BP HDL  =  0.9
25 Obesity, HDL & BP Obesity, HDL, TG, & BP + 0.9
26 Obesity Obesity, HDL & BP + 0.9
27 Obesity, HDL, TG, BP & Glucose Obesity, HDL, TG, BP & Glucose  =  0.8
28 Obesity & BP Obesity 0.8
29 Obesity & HDL Obesity & HDL  =  0.7
30 HDL & BP HDL & BP  =  0.7
31 Obesity, HDL, TG & BP Obesity, HDL, TG, BP & Glucose + 0.6
32 Obesity, BP & Glucose Obesity, HDL, BP & Glucose + 0.6
33 BP HDL, TG & BP + 0.6
34 Obesity & BP Obesity & HDL  =  0.6
35 Obesity, TG, BP & Glucose Obesity, HDL, TG, BP & Glucose + 0.6
36 Healthy Obesity & BP + 0.5
37 Obesity & HDL Obesity, HDL & BP + 0.5
38 Healthy Obesity, HDL & BP + 0.5
39 Obesity, TG & BP Obesity, TG & BP  =  0.5

These 39 most important links represent 13% of all 301 links covering 84.5% of the total flow.

“Obesity”, waist circumference: men >94 cm, women >80 cm;

“Glucose”, elevated glucose: ≥8.0 mmol/l or antidiabetic treatment;

“HDL”, decreased high-density lipoprotein cholesterol: men <1.0 mmol/l, women <1.3 mmol/l, or lipid-lowering treatment;

“TG”, elevated non-fasting triglycerides: ≥2.3 mmol/l or lipid-lowering treatment;

“BP”, elevated blood pressure: ≥130/85 mmHg or antihypertensive drug treatment.