Table 1.
Summary of Secondary Transplants with transduced human cells.
| Mouse | Group | transplanted hCD45+ (×106) cells from primary recipients |
Secondary recipients | ||
|---|---|---|---|---|---|
|
| |||||
| Doses of hCD45+(×106) cells |
GFP+ (%) | hCD45+ (%) | GFP+ in hCD45+ (%) | ||
| 1 | CTL | 1.30 | 42.3 | 0.00 | |
| 2 | CTL | 4.00 | 46.1 | 0.09 | 76.70 |
| 3 | CTL | 1.00 | 7.57 | 0.31 | 4.26 |
| 4 | CTL | 1.00 | 7.57 | 0.49 | 4.26 |
| 5 | CTL | 1.00 | 7.57 | 0.44 | 5.08 |
| 6 | WT | 0.90 | 0.42 | 0.02 | 0 |
| 7 | WT | 4.50 | 0.39 | 0.20 | 0 |
| 8 | WT | 4.50 | 0.39 | 0.06 | 0 |
| 9 | WT | 4.50 | 0.39 | 0.03 | 0 |
| 10 | N-ter | 3.35 | 22.8 | 0.02 | 0 |
| 11 | N-ter | 3.35 | 22.8 | 0 | |
| 12 | NC-ter | 5.00 | 23.6 | 0 | |
| 13 | NC-ter | 5.00 | 23.6 | 11.70 | 55.20 |
| 14 | NC-ter | 5.00 | 23.6 | 0.12 | 17.10 |
| 15 | NC-ter | 1.00 | 4.36 | 0.63 | 2.06 |