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. Author manuscript; available in PMC: 2012 Nov 15.
Published in final edited form as: J Immunol. 2012 Apr 13;188(10):5041–5053. doi: 10.4049/jimmunol.1101106

Figure 1. Antibody responses induced by AdHu5-MVA PcAMA1 prime-boost vaccination.

Figure 1

BALB/c mice (n=5) were primed with 5 × 1010 vp of AdHu5-PcAMA1 and boosted 8 weeks later with 1 × 107 pfu of MVA-PcAMA1. The AMA1-specific total IgG response against recombinant PcAMA1 ectodomain was measured by ELISA in the serum at days 14 (post-prime), 55 (pre-boost) and 70 (post-boost). Each point indicates the response from an individual mouse and the line links the mean. Significant differences between the different time-points by paired t test are shown (** P ≤ 0.01 and *** P ≤ 0.001).