. Author manuscript; available in PMC: 2012 Nov 15.

Published in final edited form as: J Immunol. 2012 Apr 13;188(10):5041–5053. doi: 10.4049/jimmunol.1101106

Table 2. Comparison of the peptide sequences containing the CD4⁺ T cell epitopes identified in AMA1 across various strains of P. chabaudi.

The table shows the sequence comparison across various P. chabaudi strains for the two CD4⁺ T cell epitopes identified in PccAS AMA1. The P16 and P79 peptides represent the αα sequence in the PccAS AMA1 vaccine. P16B and P79B represent peptides encoding the variant sequences identified in the heterologous strains. The αα shown in bold lettering differ between the homolgous and heterologous strains.

PEPTIDE	PARASITE STRAIN	SEQUENCE	VACCINE STRAIN HOMOLOGY
P16	P. chabaudi chabaudi AS	VMGKGITIQNSKVSF	Yes
P16	P. chabaudi adami 556/DK	VMGKGITIQNSKVSF	Yes
P16	P. chabaudi adami CB	VMGKGITIQNSKVSF	Yes
P16B	P. chabaudi adami DS	VMGKGITIQKSTKSF	No
P79	P. chabaudi chabaudi AS	GNGTIQFPRIFISDD	Yes
P79B	P. chabaudi adami 556/DK	GNDTIKFPRIFISDD	No
P79B	P. chabaudi adami CB	GNDTIKFPRIFISDD	No
P79B	P. chabaudi adami DS	GNDTIKFPRIFISDD	No

Table 2. Comparison of the peptide sequences containing the CD4+ T cell epitopes identified in AMA1 across various strains of P. chabaudi.

Table 2. Comparison of the peptide sequences containing the CD4⁺ T cell epitopes identified in AMA1 across various strains of P. chabaudi.