Table 3. Mean difference (95% confidence interval) in diastolic blood pressure at 8 weeks and change in diastolic blood pressure in each period of gestation by hypertensive disorders of pregnancy (N=9,930)*.
Maternal characteristics | Mean difference in DBP at 8 weeks (mmHg) |
Mean difference in average DBP change (mmHg/week): |
|||
---|---|---|---|---|---|
8-18 weeks | 18-30 weeks | 30-36 weeks | 36+ weeks | ||
Unadjusted model: | |||||
No HDP | 0 | 0 | 0 | 0 | 0 |
Gestational hypertension | 4.692 (4.096, 5.287) | 0.044 (−0.027, 0.115) | 0.113 (0.069, 0.156) | 0.401 (0.311, 0.491) | 0.805 (0.655, 0.954) |
Preeclampsia | 5.470 (4.020, 6.920) | −0.007 (−0.180, 0.166) | 0.220 (0.110, 0.331) | 1.406 (1.170, 1.642) | 2.486 (2.017, 2.956) |
Essential hypertension | 7.562 (6.455, 8.668) | 0.061 (−0.072, 0.193) | −0.055 (−0.137, 0.028) | 0.329 (0.156, 0.502) | 0.274 (−0.023, 0.572) |
Adjusted model: | |||||
No HDP | 0 | 0 | 0 | 0 | 0 |
Gestational hypertension | 3.799 (3.200, 4.398) | 0.038 (−0.035, 0.110) | 0.132 (0.088, 0.177) | 0.370 (0.278, 0.461) | 0.833 (0.680, 0.987) |
Preeclampsia | 4.674 (3.242, 6.107) | −0.028 (−0.202, 0.145) | 0.239 (0.129, 0.350) | 1.336 (1.099, 1.573) | 2.465 (1.995, 2.935) |
Essential hypertension | 6.585 (5.490, 7.679) | 0.056 (−0.077, 0.189) | −0.029 (−0.112, 0.054) | 0.312 (0.138, 0.486) | 0.333 (0.035, 0.632) |
Both models are adjusted for time to delivery; adjusted model is additionally adjusted for maternal pre-pregnancy BMI, age, parity, smoking during pregnancy, education and sex/number of fetuses
In reference category (normotensive women):
For unadjusted model:
mean DBP at 8 weeks (mmHg) = 65.393;
mean DBP change (mmHg/week): 8-18 weeks = -0.202; 18-30 weeks = 0.091; 30-36 weeks = 0.375; 36+ weeks = 1.155
For adjusted model:
mean DBP at 8 weeks (mmHg) = 65.494;
mean DBP change (mmHg/week): 8-18 weeks = -0.175; 18-30 weeks = 0.109; 30-36 weeks = 0.463; 36+ weeks = 1.252
Abbreviations: BMI body mass index; DBP diastolic blood pressure; HDP hypertensive disorder of pregnancy