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. Author manuscript; available in PMC: 2012 Nov 22.
Published in final edited form as: Circulation. 2012 Apr 23;125(20):2479–2491. doi: 10.1161/CIRCULATIONAHA.112.101246

Figure 4.

Figure 4

Platelet connexins and calcium mobilisation. Calcium mobilisation was measured in Fluo4 NW dye loaded platelets by spectrofluorimetry in the presence or absence of gap junction blockers. Platelets were stimulated with CRP-XL [0.5μg/ml, (A), 1μg/ml (B)] and fluorescence was measured for 90 seconds. Similar experiments were performed in the presence of EGTA (1mM) (E and F). The traces shown here are representative of 4 separate experiments. Data (C, D, G and H) represent mean ± S.D (n=4). The calcium levels obtained with vehicle was taken as 100%. Non-parametric Kruskal-Wallis global (p-value is shown in figure) and Dunn’s multiple comparison tests (p=<0.05) were performed.