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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Hepatology. 2012 Jun 6;56(1):281–290. doi: 10.1002/hep.25645

Figure 2.

Figure 2

Wy-14,643 protects against APAP-induced liver toxicity. Mice were fed a diet containing 0.1% Wy-14,643 24h prior to treatment with APAP. (A) Serum AST and ALT enzyme levels from control, Wy-14,643-treated, APAP-treated and Wy-14,643/APAP-treated Ppara-null mice. (B) Serum AST and ALT enzyme levels from control, Wy-14,643-treated, APAP-treated and Wy-14,643/APAP treated hPPARaPAC mice. ***p<0.001; ns, not significant.