Figure 7.
Role of UCP2 in Wy-14,643 protection against APAP-induced liver toxicity using forced expression of UCP2 in livers of wild-type mice. H&E staining of livers from wild-type mice administered Ad-Ucp2 and Ad-Cre prior to APAP treatment. Western blot of UCP2 protein in Ad-Ucp2 and Ad-Cre treated mice. Uptake of virus was monitored by PCR of Cre recombinase cDNA.