Table 1.

Blood chemistry panel, animal weights, and food consumption. Blood serum markers in animals were measured following a 4 month treatment with either a control (CTRL) or a PIO-enriched diet (PIO)

	CTRL	PIO
Calcium (mg/dL)	9.3 ± 0.39	8.5 ± 0.42
Glucose (mg/dL)	167.4 ± 19.23	169.5 ± 18.16
BUN (mg/dL)	26.4 ± 4.29	24.1 ± 5.78
ALT (U/L)	93.1 ± 27.95	43.4 ± 4.17
CK (U/L)	799.4 ± 192.73	1207.1 ± 252.65
Uric acid (mg/dL)	1.7 ± 0.24	2.2 ± 0.23
Cholesterol (mg/dL)	113.9 ± 13.40	57.4 ± 5.67#
HDL (mg/dL)	63.6 ± 7.91	33.6 ± 3.29**
LDL (mg/dL)	11.3 ± 1.46	7.9 ± 0.96
Triglyceride (mg/dL)	101.8 ± 19.42	55.4 ± 3.51*
Body weight (g)	34.6 ± 2.42	29.3 ± 0.79***
Food (g/mouse/day)	2.9 ± 0.42	2.6 ± 0.14

Abbreviations: BUN, blood urea nitrogen; ALT, alanine aminotransferase; CK, creatine kinase; HDL, high density lipoprotein; LDL, low density lipoprotein. Body weights and food intake (Food) are also presented and were averaged across the duration of the study.

^*p < 0.05,

^**p < 0.01,

^#p < 0.001

^***p < 0.0001 indicate a significant effect of PIO (T-test). Data represent Mean ± SEM.