Table 2.
Electrophysiological parameters
CTRL | PIO | |
---|---|---|
Electrode resistance (MΩ) | 117.2 ± 6.50 | 121.1 ± 7.55 |
Input resistance (MΩ) | 56.4 ± 6.37 | 66.8 ± 5.19 |
Holding current (pA) | −361.7 ± 47.04 | −276.2 ± 28.27 |
Action potential height (mV) | 68.9 ± 3.40 | 71.1 ± 3.00 |
Current injection (pA) | 230.3 ± 18.43 | 214.1 ± 18.73 |
Data represent Mean ± SEM on measure of electrode resistance, input resistance, holding current necessary to hold the cell at −70 mV, action potential height (measured from −65 mV), and intracellular current injection necessary to elicit 3 action potentials (duration 100 ms). No significant difference was found in any of these parameters across treatment groups (T-test, p > 0.05).