Table 2.
BDI Scores by eGFR and Albuminuria in Cohort Participants at Enrollment
| eGFR strata | |||||||
|---|---|---|---|---|---|---|---|
| Depressive Symptom Status |
Overall (N=3853) | eGFR (mL/min/1.73 m2) | p- valuec |
||||
| < 30 (n=719) |
30 - <40 (n=897) |
40 - <50 (n=965) |
50 - <60 (n=700) |
>=60 (n=572) |
|||
| BDI Scoreb | 6 (3 - 12) | 7 (4 - 13) | 7 (3 - 12) | 6 (2 - 11) | 5 (2 - 10) | 5 (2 - 11) | <0.001 |
| BDI Score Category | <0.001 | ||||||
| 0-10 | 2754 (71.5%) | 467 (65.0%) | 623 (69.5%) | 694 (71.9%) | 542 (77.4%) | 428 (74.8%) | |
| 11-14 | 443 (11.5%) | 109 (15.2%) | 115 (12.8%) | 112 (11.6%) | 52 (7.4%) | 55 (9.6%) | |
| 15-21 | 362 (9.4%) | 72 (10.0%) | 86 (9.6%) | 88 (9.1%) | 71 (10.1%) | 45 (7.9%) | |
| >=22 | 294 (7.6%) | 71 (9.9%) | 73 (8.1%) | 71 (7.4%) | 35 (5.0%) | 44 (7.7%) | |
| Albuminuriaa strata | |||||
|---|---|---|---|---|---|
| Depressive Symptom Status |
Overall (N=3712) | Urine ACR (mg/g) | p-valuec | ||
| < 30 (n=1598) |
30 - <300 (n=977) |
>=300 (n=1137) |
|||
| BDI Scoreb | 6 (3 - 11) | 5 (2 - 10) | 7 (3 - 11) | 7 (3 - 13) | <0.001 |
| BDI Score Category | <0.001 | ||||
| 0-10 | 2672 (72.0%) | 1221 (76.4%) | 705 (72.2%) | 746 (65.6%) | |
| 11-14 | 419 (11.3%) | 157 (9.8%) | 113 (11.6%) | 149 (13.1%) | |
| 15-21 | 350 (9.4%) | 122 (7.6%) | 100 (10.2%) | 128 (11.3%) | |
| >=22 | 271 (7.3%) | 98 (6.1%) | 59 (6.0%) | 114 (10.0%) | |
a
only includes participants with available urine ACR (3.6% missing from total cohort)
b
median (25th-75th percentile)
c
p-value for trend across categories
ACR, albumin-creatinine ratio; BDI = Beck depression inventory; eGFR = estimated glomerular filtration rate