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Percentage of tumors of myeloid and lymphoid origins from mice of indicated genotypes harboring the Eμ-N-RasG12D transgene, determined by immunogenotyping of the tumor cells and the type of infiltrated organs.
| Tumor origin |
% | |
|---|---|---|
|
PRAK+/+
(n=15) |
Myeloid* | 80.0 % |
| Lymphoid | 20.0 % | |
|
PRAK+/−
(n=33) |
Myeloid | 90.9 % |
| Lymphoid | 9.1 % | |
|
PRAK−/−
(n=9) |
Myeloid | 77.8 % |
| Lymphoid | 22.2 % | |
|
p53+/−
(n=22) |
Myeloid | 54.5 % |
| Lymphoid | 45.5 % |
