TABLE 1.
Demographics and clinical variables
| IgAN (n = 40) | Control (n = 4) | P value | |
|---|---|---|---|
| Male/female | 18/22 | 2/2 | 0.9 |
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| Age (years) | 31 ± 11 | 45 ± 16 | 0.1 |
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| BMI (kg/m2) | 23 ± 5 | 22 ± 4 | 0.9 |
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| Creatinine clearance (ml/min) | 111 ± 33 | 113 ± 23 | 0.9 |
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| SBP (mmHg) | |||
| Day | 117 ± 13 | 115 ± 19 | 0.8 |
| Night | 107 ± 13 | 105 ± 15 | 0.8 |
| 24 h | 113 ± 13 | 112 ± 18 | 0.8 |
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| DBP (mmHg) | |||
| Day | 74 ± 11 | 79 ± 16 | 0.4 |
| Night | 67 ± 10 | 70 ± 15 | 0.6 |
| 24 h | 72 ± 10 | 76 ± 16 | 0.4 |
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| Night/day ratio of MAP | 0.91 ± 0.05 | 0.89 ± 0.05 | 0.7 |
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| Night/day ratio of UNaV | 0.81 ± 0.47 | 0.80 ± 0.46 | 0.9 |
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| Fractional tubular sodium reabsorption | 0.994 ± 0.003 | 0.994 ± 0.002 | 0.9 |
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| Plasma renin activity (ng/ml per h) | 1.7 ± 1.6 | 0.7 ± 0.6 | 0.3 |
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| Plasma aldosterone concentration (pg/ml) | 135 ± 93 | 37 ± 15 | 0.08 |
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| Plasma angiotensin II (pg/ml) | 9.7 ± 5.2 | 7.5 ± 0.7 | 0.6 |
Values are means ± SD. IgAN, IgA nephropathy; MAP, mean arterial pressure (mmHg); UNaV, urinary sodium excretion rate (mmol/h).