Table 2.
Endometrial Lesions in DES-treated Mice
| Genotype | Age (weeks) | Treatment | n | No.(%) of mice with lesions | No. of lesions per mouse (mean ± SD) | Size of lesion (mm2) | Range of size (mm2) |
|---|---|---|---|---|---|---|---|
| +/− | 24 | DES | 11 | 8 (73) | 2.45 ± 2.77 | 0.11 ± 0.08 | 0.04−0.3 |
| +/− | 24 | Oil | 9 | 8 (88.9) | 9.78 ± 5.91 | 0.19 ± 0.16 | 0.04−0.64 |
| +/− | 32 | DES | 10 | 8 (80) | 6.70 ± 7.06⁎ | 0.14 ± 0.12 | 0.03−0.48 |
| +/− | 32 | Oil | 9 | 9 (100) | 18.56 ± 8.57⁎ | 0.22 ± 0.12 | 0.04−0.75 |
| +/+ | 24 | DES | 9 | 3 (33) | 1.22 ± 1.99 | 0.03 ± 0.01 | 0.02−0.04 |
| +/+ | 32 | DES | 11 | 4 (36) | 1.18 ± 1.83 | 0.11 ± 0.14 | 0.04−0.48 |
⁎
P = 0.0072, difference was statistically significant.