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Endometrial Lesions in Pten+/−ER−/− Mice and Littermates
| Genotype | Age (weeks) | n | Mice with lesions | Mice with in situ CA | Mice with invasion | Lesions per mouse (mean ± SD) | Size of lesion (mm2) |
|---|---|---|---|---|---|---|---|
| Pten+/+ER+/+ | 32 | 2 | 0 | 0 | 0 | ||
| Pten+/+ER−/− | 32 | 3 | 0 | 0 | 0 | ||
| Pten+/−ER+/+ | 32 | 10 | 10/10 | 0 | 0 | 18.56 ± 8.57 | 0.22 ± 0.12⁎ |
| Pten+/−ER+/− | 32 | 7 | 7/7 | 0 | 0 | 5.5 ± 0.71 | 0.13 ± 0.08⁎ |
| Pten+/−ER−/− | 32 | 9 | 8/9 | 2/8 | 2/8 | 9.57 ± 6.78 | 0.51 ± 0.84 |
P = 0.104, difference was not statistically significant.
