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. 2012 Jan 31;40(10):4412–4421. doi: 10.1093/nar/gks007

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© The Author(s) 2012. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Snf2 intercalates between the DNA gyre and histone octamer, and Isw2 does not. (A). The DNA footprinting pattern of the 601 nucleosome with hydroxyl radical is shown for the DNA strand in which the photoreactive group is also placed. The numbers indicate the specific site at which a photoreactive group is attached and those numbers in gray are on the exposed side of the nucleosomal DNA. (B and C) The relative efficiency of Snf2 (B) and Isw2 (C) crosslinked to DNA is plotted versus DNA location. The light gray line denotes the positions on the exposed side of the nucleosome and the black line denotes the positions on the histone octamer side of the DNA. The numbers shown on the x-axis correspond to the number of nucleotides from the dyad axis. Those positions shown as a darker gray line are in the extranucleosomal DNA region.