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. 2012 Jun 20;5:76. doi: 10.3389/fnmol.2012.00076

Figure 7.

Figure 7

Serotonin immunohistochemistry in the early postnatal somatosensory cortex. (A,B). Serotonin immunostaining highlighted the distribution of TC axons in the developing cortex. At P2, at a time barrel units are not yet formed, immunostaining revealed a uniform distribution of axons in both wild type and mutant mice. (C,D). At P6, serotonin immunoreactivity clustered in layer IV in a manner reminiscent of barrels (highlighted in the inset) in wild type animals (C). In P6 NCAM null mutant mice, TC axons also localized to layer IV but showed a continuous distribution (D). Confocal optical sections. IV, cortical layer IV. Bar: 100 μm.