Table 3.

Associations Among Cardioembolism, Large-Artery Atherosclerosis, Small-Vessel Occlusion and Normal Controls

		CE (n=33) vs. Control (n=267)				LAA (n=123) vs. Control (n=267)			SVO (n=395) vs. Control (n=267)
		MAF				MAF			MAF
Gene	SNP	CE	Controls	p-Value	Statistical power (%)	LAA	Controls	p-Value	SVO	Controls	p-Value	Statistical power (%)
NPPB	rs198389A/G	0.156	0.125	0.822	45.46	0.135	0.125	0.564	0.133	0.125	0.373	100
	rs5227G/T	0.000	0.000	—		0.000	0.000	—	0.000	0.000	—
	rs35640285G/T	0.000	0.000	—		0.000	0.000	—	0.000	0.000	—
NPPA	rs61757273G/T	0.091	0.068	0.415	30.06	0.095	0.068	0.147	0.065	0.068	0.169	99.99
	rs198373A/G	0.000	0.002	—		0.000	0.002	—	0.010	0.002	0.041	18.56
	rs198372G/A	0.000	0.002	—		0.000	0.002	—	0.010	0.002	0.040	18.56
	rs5063G/A	0.076	0.099	0.200	30.12	0.111	0.099	0.438	0.090	0.099	0.647	99.99
	rs5065T/C	0.030	0.006	0.002	7.29	0.008	0.006	0.669	0.004	0.006	0.952	25.55
	rs5067A/G	0.030	0.006	0.002	7.29	0.008	0.006	0.674	0.004	0.006	0.945	25.55

Bold value indicates the statistical significance of P<0.05.

p-Values of additive model were obtained by logistic analysis adjusted for age, sex, and histories of hypertension and diabetes mellitus as covariables.