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. Author manuscript; available in PMC: 2012 Jun 20.
Published in final edited form as: IEEE Trans Med Imaging. 2009 Feb 20;28(8):1296–1307. doi: 10.1109/TMI.2009.2014863

Fig. 4.

Fig. 4

Comparison of ROC curves for our multiseed method (solid lines with circles) and the single-seed method (with spatial noise also considered, dashed lines) at different SNRs, showing significantly improved performance using multiple seeds. Note: The TPR and FPR for the single-seed case are computed as below: M is the total number of voxels; Let i = 1, 2 be the seed index. Suppose: ni (i = 1, 2) is the number of voxels correctly detected as significant; Ni (i = 1, 2) is the number of voxels with added type i connectivity; mi (i = 1, 2) is the number of voxels incorrectly detected as significant. Therefore, the combined TPR and FPR used in the ROC plots for the single-seed case are: TPR = (n1 + n2)/(N1 + N2) and FPR = (m1 + m2)/(M − N1 − N2)